A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells

Surendra K. Ravula; Diane S. Lidke; Janet M. Oliver; Darren W. Branch; Gregory Kaduchak; Conrad D. James; Igal Brener

doi:10.1109/SENSOR.2007.4300227

A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells

Surendra K. Ravula
, Diane S. Lidke
, Janet M. Oliver
, Darren W. Branch
, Gregory Kaduchak
, Conrad D. James
, Igal Brener

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Scopus citations

Abstract

In this paper we describe our work that uses acoustics and dielectrophoresis to move particles/cells in microsystems. These particle manipulation technologies are used to create a high throughput system for spatiotemporal analyses of signaling within biological cells. The fabrication scheme and the focusing characteristics of the system are presented. The system allows the focusing characteristics to be tuned and optimized by changing the frequency of actuation for both the dielectrophoretic and piezoelectric electrodes. In addition to system characterization, we present initial data positioning rat basophilic leukemia (RBL) cells along the diffusion boundary of two different flow streams. ©2007 IEEE.

Original language	English
Title of host publication	TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems
Pages	703-706
Number of pages	4
DOIs	https://doi.org/10.1109/SENSOR.2007.4300227
State	Published - Dec 1 2007
Externally published	Yes

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10.1109/SENSOR.2007.4300227

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Ravula, S. K., Lidke, D. S., Oliver, J. M., Branch, D. W., Kaduchak, G., James, C. D., & Brener, I. (2007). A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells. In TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems (pp. 703-706) https://doi.org/10.1109/SENSOR.2007.4300227

@inproceedings{cc6eb0f69db442e4a9972583c463dc65,

title = "A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells",

abstract = "In this paper we describe our work that uses acoustics and dielectrophoresis to move particles/cells in microsystems. These particle manipulation technologies are used to create a high throughput system for spatiotemporal analyses of signaling within biological cells. The fabrication scheme and the focusing characteristics of the system are presented. The system allows the focusing characteristics to be tuned and optimized by changing the frequency of actuation for both the dielectrophoretic and piezoelectric electrodes. In addition to system characterization, we present initial data positioning rat basophilic leukemia (RBL) cells along the diffusion boundary of two different flow streams. {\textcopyright}2007 IEEE.",

author = "Ravula, \{Surendra K.\} and Lidke, \{Diane S.\} and Oliver, \{Janet M.\} and Branch, \{Darren W.\} and Gregory Kaduchak and James, \{Conrad D.\} and Igal Brener",

year = "2007",

month = dec,

day = "1",

doi = "10.1109/SENSOR.2007.4300227",

language = "English",

isbn = "1424408423",

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booktitle = "TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems",

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Ravula, SK, Lidke, DS, Oliver, JM, Branch, DW, Kaduchak, G, James, CD & Brener, I 2007, A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells. in TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems. pp. 703-706. https://doi.org/10.1109/SENSOR.2007.4300227

A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells. / Ravula, Surendra K.; Lidke, Diane S.; Oliver, Janet M. et al.
TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems. 2007. p. 703-706.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells

AU - Ravula, Surendra K.

AU - Lidke, Diane S.

AU - Oliver, Janet M.

AU - Branch, Darren W.

AU - Kaduchak, Gregory

AU - James, Conrad D.

AU - Brener, Igal

PY - 2007/12/1

Y1 - 2007/12/1

N2 - In this paper we describe our work that uses acoustics and dielectrophoresis to move particles/cells in microsystems. These particle manipulation technologies are used to create a high throughput system for spatiotemporal analyses of signaling within biological cells. The fabrication scheme and the focusing characteristics of the system are presented. The system allows the focusing characteristics to be tuned and optimized by changing the frequency of actuation for both the dielectrophoretic and piezoelectric electrodes. In addition to system characterization, we present initial data positioning rat basophilic leukemia (RBL) cells along the diffusion boundary of two different flow streams. ©2007 IEEE.

AB - In this paper we describe our work that uses acoustics and dielectrophoresis to move particles/cells in microsystems. These particle manipulation technologies are used to create a high throughput system for spatiotemporal analyses of signaling within biological cells. The fabrication scheme and the focusing characteristics of the system are presented. The system allows the focusing characteristics to be tuned and optimized by changing the frequency of actuation for both the dielectrophoretic and piezoelectric electrodes. In addition to system characterization, we present initial data positioning rat basophilic leukemia (RBL) cells along the diffusion boundary of two different flow streams. ©2007 IEEE.

UR - https://www.scopus.com/pages/publications/50049134012

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DO - 10.1109/SENSOR.2007.4300227

M3 - Conference contribution

SN - 1424408423

SN - 9781424408429

SP - 703

EP - 706

BT - TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems

ER -

Ravula SK, Lidke DS, Oliver JM, Branch DW, Kaduchak G, James CD et al. A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells. In TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems. 2007. p. 703-706 doi: 10.1109/SENSOR.2007.4300227

A microfluidic platform with micro acoustics and dielectrophoresis for high throughput analyses of spatiotemporal signaling in biological cells

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