Frictional properties of native and functionalized type i collagen thin films

Koo Hyun Chung; Antony K. Chen; Christopher R. Anderton; Kiran Bhadriraju; Anne L. Plant; Brian G. Bush; Robert F. Cook; Frank W. Delrio

doi:10.1063/1.4824685

Frictional properties of native and functionalized type i collagen thin films

Koo Hyun Chung
, Antony K. Chen
, Christopher R. Anderton
, Kiran Bhadriraju
, Anne L. Plant
, Brian G. Bush
, Robert F. Cook
, Frank W. Delrio

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Frictional properties of native and fibronectin (FN)-functionalized type I collagen (COL) thin films were studied via atomic force microscopy. The COL lateral contact stiffness was dependent only on the hydration state, indicating that shear deformation was invariant with FN. In contrast, the COL coefficient of friction and shear strength varied with both functionalization and hydration state. The changes in shear strength were found to correlate well with changes in mean cell spread area on the same thin films, suggesting that shear strength is a better indicator of cell spreading than heretofore considerations of film, and thus extracellular matrix, stiffness alone. © 2013 AIP Publishing LLC.

Original language	English
Journal	Applied Physics Letters
Volume	103
Issue number	14
DOIs	https://doi.org/10.1063/1.4824685
State	Published - Sep 30 2013
Externally published	Yes

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@article{7289730cf0464c1a813107798d0acb55,

title = "Frictional properties of native and functionalized type i collagen thin films",

abstract = "Frictional properties of native and fibronectin (FN)-functionalized type I collagen (COL) thin films were studied via atomic force microscopy. The COL lateral contact stiffness was dependent only on the hydration state, indicating that shear deformation was invariant with FN. In contrast, the COL coefficient of friction and shear strength varied with both functionalization and hydration state. The changes in shear strength were found to correlate well with changes in mean cell spread area on the same thin films, suggesting that shear strength is a better indicator of cell spreading than heretofore considerations of film, and thus extracellular matrix, stiffness alone. {\textcopyright} 2013 AIP Publishing LLC.",

author = "Chung, \{Koo Hyun\} and Chen, \{Antony K.\} and Anderton, \{Christopher R.\} and Kiran Bhadriraju and Plant, \{Anne L.\} and Bush, \{Brian G.\} and Cook, \{Robert F.\} and Delrio, \{Frank W.\}",

year = "2013",

month = sep,

day = "30",

doi = "10.1063/1.4824685",

language = "English",

volume = "103",

journal = "Applied Physics Letters",

issn = "0003-6951",

publisher = "American Institute of Physics",

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T1 - Frictional properties of native and functionalized type i collagen thin films

AU - Chung, Koo Hyun

AU - Chen, Antony K.

AU - Anderton, Christopher R.

AU - Bhadriraju, Kiran

AU - Plant, Anne L.

AU - Bush, Brian G.

AU - Cook, Robert F.

AU - Delrio, Frank W.

PY - 2013/9/30

Y1 - 2013/9/30

N2 - Frictional properties of native and fibronectin (FN)-functionalized type I collagen (COL) thin films were studied via atomic force microscopy. The COL lateral contact stiffness was dependent only on the hydration state, indicating that shear deformation was invariant with FN. In contrast, the COL coefficient of friction and shear strength varied with both functionalization and hydration state. The changes in shear strength were found to correlate well with changes in mean cell spread area on the same thin films, suggesting that shear strength is a better indicator of cell spreading than heretofore considerations of film, and thus extracellular matrix, stiffness alone. © 2013 AIP Publishing LLC.

AB - Frictional properties of native and fibronectin (FN)-functionalized type I collagen (COL) thin films were studied via atomic force microscopy. The COL lateral contact stiffness was dependent only on the hydration state, indicating that shear deformation was invariant with FN. In contrast, the COL coefficient of friction and shear strength varied with both functionalization and hydration state. The changes in shear strength were found to correlate well with changes in mean cell spread area on the same thin films, suggesting that shear strength is a better indicator of cell spreading than heretofore considerations of film, and thus extracellular matrix, stiffness alone. © 2013 AIP Publishing LLC.

UR - https://www.scopus.com/pages/publications/84885661754

U2 - 10.1063/1.4824685

DO - 10.1063/1.4824685

M3 - Article

SN - 0003-6951

VL - 103

JO - Applied Physics Letters

JF - Applied Physics Letters

IS - 14

ER -

Frictional properties of native and functionalized type i collagen thin films

Abstract

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