Heterocyclic aminoboron compounds as antituberculosis agents

Lachlan S. Campbell-Verduyn; Eric G. Bowes; Haoxin Li; Alain M. Vallée; Christopher M. Vogels; Andreas Decken; Christopher A. Gray; Stephen A. Westcott

doi:10.1002/hc.21141

Heterocyclic aminoboron compounds as antituberculosis agents

Lachlan S. Campbell-Verduyn
, Eric G. Bowes
, Haoxin Li
, Alain M. Vallée
, Christopher M. Vogels
, Andreas Decken
, Christopher A. Gray
, Stephen A. Westcott

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

We have examined six boron compounds for their potential antituberculosis activities. Addition of 2-formylphenyl pinacol boronate ester to tetraamine derivatives gave three new aminoboron compounds, which were elementally pure when obtained, and one example was characterized by a single crystal X-ray diffraction study. Heterocyclic aminoboron compounds 1-4 showed moderate degrees of antimycobacterial activity against Mycobacterium tuberculosis.

Original language	English
Pages (from-to)	100-106
Number of pages	7
Journal	Heteroatom Chemistry
Volume	25
Issue number	2
DOIs	https://doi.org/10.1002/hc.21141
State	Published - Mar 2014
Externally published	Yes

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10.1002/hc.21141

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title = "Heterocyclic aminoboron compounds as antituberculosis agents",

abstract = "We have examined six boron compounds for their potential antituberculosis activities. Addition of 2-formylphenyl pinacol boronate ester to tetraamine derivatives gave three new aminoboron compounds, which were elementally pure when obtained, and one example was characterized by a single crystal X-ray diffraction study. Heterocyclic aminoboron compounds 1-4 showed moderate degrees of antimycobacterial activity against Mycobacterium tuberculosis.",

author = "Campbell-Verduyn, \{Lachlan S.\} and Bowes, \{Eric G.\} and Haoxin Li and Vall{\'e}e, \{Alain M.\} and Vogels, \{Christopher M.\} and Andreas Decken and Gray, \{Christopher A.\} and Westcott, \{Stephen A.\}",

year = "2014",

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doi = "10.1002/hc.21141",

language = "English",

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T1 - Heterocyclic aminoboron compounds as antituberculosis agents

AU - Campbell-Verduyn, Lachlan S.

AU - Bowes, Eric G.

AU - Li, Haoxin

AU - Vallée, Alain M.

AU - Vogels, Christopher M.

AU - Decken, Andreas

AU - Gray, Christopher A.

AU - Westcott, Stephen A.

PY - 2014/3

Y1 - 2014/3

N2 - We have examined six boron compounds for their potential antituberculosis activities. Addition of 2-formylphenyl pinacol boronate ester to tetraamine derivatives gave three new aminoboron compounds, which were elementally pure when obtained, and one example was characterized by a single crystal X-ray diffraction study. Heterocyclic aminoboron compounds 1-4 showed moderate degrees of antimycobacterial activity against Mycobacterium tuberculosis.

AB - We have examined six boron compounds for their potential antituberculosis activities. Addition of 2-formylphenyl pinacol boronate ester to tetraamine derivatives gave three new aminoboron compounds, which were elementally pure when obtained, and one example was characterized by a single crystal X-ray diffraction study. Heterocyclic aminoboron compounds 1-4 showed moderate degrees of antimycobacterial activity against Mycobacterium tuberculosis.

UR - https://www.scopus.com/pages/publications/84896405503

U2 - 10.1002/hc.21141

DO - 10.1002/hc.21141

M3 - Article

SN - 1042-7163

VL - 25

SP - 100

EP - 106

JO - Heteroatom Chemistry

JF - Heteroatom Chemistry

IS - 2

ER -

Heterocyclic aminoboron compounds as antituberculosis agents

Abstract

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