Three-dimensional tracking of individual quantum dots

Guillaume A. Lessard; Peter Marvin Goodwin; James Henry Werner

doi:10.1063/1.2819074

Three-dimensional tracking of individual quantum dots

Guillaume A. Lessard
, Peter Marvin Goodwin
, James Henry Werner

Los Alamos National Laboratory

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Abstract

We describe an instrument that extends the state of the art in a single-molecule tracking technology, allowing extended observations of single fluorophores and fluorescently labeled proteins as they undergo directed and diffusive transport in three dimensions. We demonstrate three-dimensional tracking of individual quantum dots undergoing diffusion for durations of over a second at velocities comparable to those of intracellular signaling processes.

Original language	English
Article number	224106
Journal	Applied Physics Letters
Volume	91
Issue number	22
DOIs	https://doi.org/10.1063/1.2819074
State	Published - Dec 6 2007

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title = "Three-dimensional tracking of individual quantum dots",

abstract = "We describe an instrument that extends the state of the art in a single-molecule tracking technology, allowing extended observations of single fluorophores and fluorescently labeled proteins as they undergo directed and diffusive transport in three dimensions. We demonstrate three-dimensional tracking of individual quantum dots undergoing diffusion for durations of over a second at velocities comparable to those of intracellular signaling processes.",

author = "Lessard, \{Guillaume A.\} and Goodwin, \{Peter Marvin\} and Werner, \{James Henry\}",

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AU - Lessard, Guillaume A.

AU - Goodwin, Peter Marvin

AU - Werner, James Henry

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N2 - We describe an instrument that extends the state of the art in a single-molecule tracking technology, allowing extended observations of single fluorophores and fluorescently labeled proteins as they undergo directed and diffusive transport in three dimensions. We demonstrate three-dimensional tracking of individual quantum dots undergoing diffusion for durations of over a second at velocities comparable to those of intracellular signaling processes.

AB - We describe an instrument that extends the state of the art in a single-molecule tracking technology, allowing extended observations of single fluorophores and fluorescently labeled proteins as they undergo directed and diffusive transport in three dimensions. We demonstrate three-dimensional tracking of individual quantum dots undergoing diffusion for durations of over a second at velocities comparable to those of intracellular signaling processes.

UR - https://www.scopus.com/pages/publications/36549058177

U2 - 10.1063/1.2819074

DO - 10.1063/1.2819074

M3 - Article

SN - 0003-6951

VL - 91

JO - Applied Physics Letters

JF - Applied Physics Letters

IS - 22

M1 - 224106

ER -

Three-dimensional tracking of individual quantum dots

Abstract

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